Sucralose

25kg/Carton

SKU: 5000kg 类别:
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INQUIRY
Description Sucralose is an intense organochlorine artificial sweetener.
In Vivo The results show that Sucralose induces significant increased incidence of all hematopoietic neoplasias in male mice exposed to 2,000 (p≤0.01), and 16,000 ppm (p≤0.01), with a significant dose-related relationship (p≤0.01). Microscopically, most of the neoplasias among male mice treated with Sucralose at 2,000 to 16,000 ppm are leukemias involving lungs, liver, spleen, lymph nodes, and bone marrow with diffuse permeation of vessels and extensive infiltration of adjacent tissues[1].
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg

 

1 mM 2.5149 mL 12.5745 mL 25.1490 mL
5 mM 0.5030 mL 2.5149 mL 5.0298 mL
10 mM 0.2515 mL 1.2575 mL 2.5149 mL

Please refer to the solubility information to select the appropriate solvent.

Animal Administration
[1]
Sucralose is pulverized in a standard pelleted diet at concentrations 0, 500, 2,000, 8,000, and 16,000 ppm and is administered to five groups of male (n=117, 114, 90, 66, and 70, respectively) and five groups female (n=102, 105, 60, 65, and 64, respectively) Swiss mice from the 12th day of fetal life until death[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight 397.63
Formula C₁₂H₁₉Cl₃O₈
CAS No. 56038-13-2
SMILES ClC[C@]1(O[C@H](CCl)[C@@H](O)[C@@H]1O)O[C@H]([C@@H]([C@@H](O)[C@H]2Cl)O)O[C@@H]2CO
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month

 

Shipping Room temperature in continental US; may vary elsewhere
Solvent & Solubility H2O: 53.3 mg/mL

* “<1 mg/mL” means slightly soluble or insoluble. “≥” means soluble, but saturation unknown.

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Sucralose-COA wharton

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