Norboletone

1kg/tin 5kg/carton

SKU: 50kg 类别:
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INQUIRY
Description Norboletone (Norbolethone) is an anabolic steroid for the treatment of short stature but never marketed.
In Vivo Norboletone can protect the rat against the production of multiple intestinal ulcers and peritonitis by indsmethacirp. Norboletone at 10 mg dosage level offers complete protection of indomethacin produced gastrointestinal ulcers[1]. Norbolethone impairs the ability to excrete the foreign dyes and to secrete bile[2].
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg

 

1 mM 3.1598 mL 15.7988 mL 31.5976 mL
5 mM 0.6320 mL 3.1598 mL 6.3195 mL
10 mM 0.3160 mL 1.5799 mL 3.1598 mL

Please refer to the solubility information to select the appropriate solvent.

Animal Administration
[1]
Rats: Female rats receive indomethacin at the dosage of 1 mg in 0.2 mL water, subcutaneously, once daily. Group I is not otherwise treated, group 2 receives 2 mg of spironslactoare, and groups 3 and 4 are given 2 and 10 mg of Norboletone respectively, in 1 mL water, twice daily by a stomach tube, beginning on the fourth day before initiation of indomethacin treatment. The experiment is terminated on the sixth day of indomethacin treatment by killing the survivors with chIoroform. At that time, the incidence and severity of the intestinal ulcers and peritonitis are determined[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight 316.48
Formula C₂₁H₃₂O₂
CAS No. 797-58-0
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month

 

Shipping Room temperature in continental US; may vary elsewhere
Solvent & Solubility DMSO

* “<1 mg/mL” means slightly soluble or insoluble. “≥” means soluble, but saturation unknown.

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Norboletone-COA wharton

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