Pregnenolone

1kg/tin 5kg/carton

SKU: 50kg 类别:
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INQUIRY
Description Pregnenolone is an endogenous steroid hormone for inhibition of M1 receptor and M3 receptor-mediated currents with IC50 of 11.4 μM and 6.0 μM, respectively. Target: M1 receptor; M3 receptor Pregnenolone is an endogenous steroid hormone involved in the steroidogenesis of progestogens, mineralocorticoids, glucocorticoids, androgens, and estrogens, as well as the neuroactive steroids. Pregnenolone and its sulfate, like DHEA and its sulfate and progesterone, belong to the group of neurosteroids that are found in high concentrations in certain areas of the brain, and are synthesized there. Neurosteroids affect synaptic functioning, are neuroprotective, and enhance myelinization. Pregnenolone and its sulfate ester are under investigation for their potential to improve cognitive and memory functioning. Pregnenolone is also being considered as a potential treatment for schizophrenia.
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg

 

1 mM 3.1598 mL 15.7988 mL 31.5976 mL
5 mM 0.6320 mL 3.1598 mL 6.3195 mL
10 mM 0.3160 mL 1.5799 mL 3.1598 mL

Please refer to the solubility information to select the appropriate solvent.

Molecular Weight 316.48
Formula C₂₁H₃₂O₂
CAS No. 145-13-1
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month

 

Shipping Room temperature in continental US; may vary elsewhere
Solvent & Solubility 10 mM in DMSO

* “<1 mg/mL” means slightly soluble or insoluble. “≥” means soluble, but saturation unknown.

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Pregnenolone-COA wharton

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